methods for treating allergic diseases and other inflammatory conditions, and for treating or preventing disease, compound, pharmaceutical composition, and use of a compound
CHARLOTTE JANE MITCHELL,DIANE MARY COE,HELENE BAZIN-LEE,LINOS LAZARIDES,NAIMISHA TRIVEDI,STEPHEN ALLAN SMITH
申请号：
BRPI0917013
公开号：
BRPI0917013A2
申请日:
2009.08.07
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
Compounds of formula (I): wherein R 1 is C 1-6 alkylamino, or C 1-6 alkoxy； R 2 is a group having the structure: n is an integer having a value of 1 to 6； Het is a 6-membered saturated heterocycle containing one nitrogen atom wherein Het is attached to the -(CH 2 ) n - moiety at any carbon atom of the heterocycle； R 3 is hydrogen, C 1-8 alkyl, or C 3-7 cycloalkylC 0-6 alkyl； and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
