GÉNÉRATION DE PROMOTEURS SYNTHÉTIQUES INDUCTIBLES PAR ACTIVATION DE LYMPHOCYTES T MAMMIFÈRES (SYN + PRO) POUR AMÉLIORER LE TRAITEMENT DES LYMPHOCYTES T
Seattle Children's Hospital (DBA Seattle Children's Research Institute)
发明人:
申请号:
EP18803169.4
公开号:
EP3624814A1
申请日:
2018.05.15
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Aspects of the invention described herein relate to methods of making and using inducible promoters for transgene expression. The inducible promoters are derived from the NFAT-RE inducible system and are used to improve or enhance T cell survival and proliferation.