THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
发明人:
Billy M. Hargis,Neil R. Pumford,Marion Morgan,Srichaitanya Shivaramaiah,Guillermo Tellez-Isaias,Amanda Wolfenden
申请号：
US16379535
公开号：
US20190231869A1
申请日:
2019.04.09
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Adjuvants comprising chitosan cross-linked with an aldehyde or mannosylated chitosan are provided herein. Methods of making the adjuvants and methods of combining or linking the adjuvants with antigens are also provided. The adjuvant-antigen combinations can be used in vaccine formulations and the vaccine formulations can be used in methods to vaccinate animals against the source of the antigen or to enhance the immune response in a subject.
