SALMANS, Joshua Reginald,ALEXANDER, Svetlana,BARBOUR, Robin,HIGAKI, Jeffrey N.,NIJJAR, Tarlochan S.
申请号:
SG11202002489Y
公开号:
SG11202002489YA
申请日:
2018.10.05
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
The invention provides antibodies that specifically bind to transthyretin (TTR). The antibodies can be used for treating or effecting prophylaxis of diseases or disorders associated with TTR accumulation or accumulation of TTR deposits (e.g., TTR amyloidosis). The antibodies can also be used for diagnosing TTR amyloidosis and inhibiting or reducing aggregation of TTR, and for monitoring the efficacy of TTR therapies, among other applications.