Wuhan QR Pharmaceuticals Co., Ltd.;Wuhan LL Science And Technology Development Co., Ltd.
发明人:
申请号：
EP18789939.8
公开号：
EP3611160A1
申请日:
2018.04.27
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present disclosure belongs to the field of chemical synthesis, and in particular relates to an ammonium carboxylate compound, a crystalline form and an amorphous form, and a preparation method thereof. The present disclosure prepares the compound and the crystalline form I and its single crystal, amorphous form and crystalline form II thereof. The compound, the crystalline forms, the single crystal and the amorphous form can stably exist and exhibit good solid forms, suitable for medicine-making. Furthermore, these products possess high purity and less single impurity. Moreover, the preparation methods of the present disclosure are easy to implement due to the simple processes with mild reaction conditions, and could produce products of high yield and high purity without complex purification steps. Furthermore, the preparation methods may facilitate safety, environmental protection, and industrial production.
