TITBALL, Richard William,BOKORI-BROWN, Monika,MORCRETTE, Helen,LEWIS, Nicholas Peter
申请号：
AU2019227860
公开号：
AU2019227860A1
申请日:
2019.03.01
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
This invention relates to methods and compositions for detecting, diagnosing, preventing, treating or ameliorating the symptoms of a demyelinating condition selected from: : enterotoxemia (ET), multiple sclerosis(MS), clinically definite MS (CDMS), clinically isolated syndrome (CIS),neuromyelitis optica spectrum disorder(NMOSD),optic neuritis(ON), neuromyelitis optica (NMO), myelitis,myelitis, transverse myelitis (TM), a disease or condition characterised by the increase or presence of antibodies against aquaporin-4(AQP-4) and/or astrocyte damage,and acute disseminated encephalomyelitis (ADEM) in a human or animal subject in need. The methods comprise administering to the subject a composition comprising an effective amount of an agent that directly or indirectly interfereswith epsilontoxin (ETX) produced by
