The Board of Trustees of the Leland Stanford Junior University
发明人:
Lee Meredith M.,Levi Jelena,Zehnder James L.,Harris, Jr. James S.
申请号：
US201514752144
公开号：
US9986941(B2)
申请日:
2015.06.26
申请国别(地区):
美国
年份:
2018
代理人:
Lumen Patent Firm
摘要：
Improved monitoring of one or more blood coagulation factors is provided. Factor-specific molecular probes having a dye-quencher arrangement are employed. In preferred embodiments, a compact integrated optical source and detector device is used for fluorescence measurements. Continuous and real-time monitoring of the activity of one or multiple blood factors is provided. Such real-time information can be used to automatically control delivery of drugs such as coagulants and/or blood thinners.
