HETEROCYCLIC COMPOUNDS AS POSITIVE MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR 2 (MGLU2 RECEPTOR)农业专利-农业学术服务平台

发明人:: GENESTE, HERVE,赫夫吉尼斯特,赫夫吉尼斯特,SAUER, DARYL,达尔索儿,達爾索兒,BRAJE, WILFRIED,威尔弗瑞德布拉杰,威爾弗瑞德布拉傑,AMBERG, WILHELM,威惠牡艾姆柏格,威惠牡艾姆柏格,MEZLER, MARIO,马力欧梅思乐,馬力歐梅思樂,BAKKER, MARGARETHA HENRICA MARIA,玛格芮莎亨瑞卡玛丽

摘要：: The present invention relates to heterocyclic compounds which are positive modulators of metabotropic glutamate receptor. The present invention also relates to the use of these compounds for preparing a pharmaceutical composition and to a method of treating a medical disorder, selected from neurological and psychiatric disorders associated with glutamate dysfunction.本發明係關於作為代謝性麩胺酸受體之正向調節劑之雜環化合物。本發明亦係關於該等化合物用於製備醫藥組合物之用途及一種治療選自與麩胺酸功能異常相關之神經及精神病症之醫學病症的方法。