Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation using a combination of an inhibitor of a mutant IDH1 enzyme and an AML induction and consolidation therapy.Linvention concerne des méthodes et des compositions pour traiter des cancers chez des patients porteurs dune mutation IDH1 à laide dune combinaison dun inhibiteur dune enzyme IDH1 mutante et dune thérapie dinduction et de consolidation dune LAM.