METHOD FOR DELIVERING AGENTS INTO CELLS USING BACTERIAL TOXINS

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专利权人:

President and Fellows of Harvard College

发明人:

Pentelute, Brad L.,Collier, Robert J.

申请号：

AU2016200031

公开号：

AU2016200031A1

申请日:

2016.01.05

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

#$%^&*AU2016200031A120160128.pdf#####ABSTRACT The invention provides compositions and methods for delivering a bioactive moiety comprising at least one non-natural component into a cell cytosol of an eukaryotic cell. The bioactive moiety is linked to an A component of a bacterial toxin, a functional wild-type or modified fragment thereof, or an A component surrogate or mimetic. For delivery, the cell is contacted with the linked bioactive moiety and a corresponding B component of the bacterial toxin or a functional fragment thereof.

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中国工程科技知识中心

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http://www.ckcest.cn/home/