The Board of Trustees of the Leland Stanford Junior University;Bolt Biotherapeutics, Inc.
发明人:
Michael Nathaniel Alonso,Edgar George Engleman,Shelley Erin Ackerman,Justin Kenkel,Arthur Lee,David Y. Jackson
申请号:
US16817864
公开号:
US20200206357A1
申请日:
2020.03.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention provides an immunoconjugate comprising an antibody construct which includes an antigen binding domain and an Fc domain, an adjuvant moiety, and a linker, wherein each adjuvant moiety is covalently bonded to the antibody via the linker. Methods for treating cancer with the immunoconjugates of the invention are also described.