The purpose of the present invention is to provide formulation technology with which it is possible to prevent a reduction over time in the kinematic viscosity of an aqueous liquid medicine containing hypromellose and/or hydroxyethyl cellulose. It is possible to prevent a reduction over time in the viscosity of an aqueous liquid medicine compounded by combining hypromellose and/or hydroxyethyl cellulose and polyoxyethylene-hydrogenated castor oil and/or polyoxyl stearate.本發明之目的係提供一種於含有羥丙基甲基纖維素及/或羥乙基纖維素之水性液劑中，抑制經時性動黏度降低之製劑技術。一種水性液劑，係將羥丙基甲基纖維素及/或羥乙基纖維素，與聚氧乙烯氫化蓖麻油及/或聚氧乙烯硬脂酸酯組合而摻合者，其可抑制經時性黏度降低。
