A wireless biometric lead set in which one or more biometric sensors are hermetically sealed in a package. The lead set may contain multiple such sensors and packages, with other components to operate the lead set, such as a power source, a transmitter, and a charging device. Such a lead set may be sterilized for reuse and may be configured to easily fit into existing medical facility work flows. The lead set may automatically, associate with a specific monitoring device. That monitoring device may selectively process data transmitted from the associated lead set. Further, low power operation may be achieve via multiple operating modes, such as modes in which no actions are performed, samples are taken and accumulated, or accumulated samples are transmitted. An interface device may allow the lead set to be used with a conventional monitoring device.