Process for synthesis of tritiated and deuterated thiorphan and acetorphan

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专利权人:

Mohammand R. Masjedizadeh

发明人:

Mohammand R. Masjedizadeh,Shao-Yong Wu

申请号：

US12316946

公开号：

US08101665B2

申请日:

2008.12.17

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Methods for preparing tritium or deuterium labeled thiorphan comprising reacting a compound of formula jwherein m is from 1 to 5 and X is halo, with Z2 wherein Z is tritium or deuterium, in the presence of a catalyst, to form a compound of formula kwherein n is from 1 to 5, provided that n is less than or equal to m.

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