Patricio Manuel V. A. Soares Da Silva,David Alexander Learmonth,Alexander Beliaev
申请号：
US15454201
公开号：
US20170369478A1
申请日:
2017.03.09
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compounds of formula I and a method for their preparation are described, where R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group； R4 signifies -alkyl-aryl or alkyl heteroaryl； X signifies CH2, oxygen atom or sulphur atom； n is 2 or 3； including the individual (R)- and (S)-enantiomers or mixtures of enantiomers thereof； and including pharmaceutically acceptable salts and esters thereof. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure.
