Eugene M. Chow,David K. Biegelsen,Michael I Recht,Fatemeh Primoradi,Felicia Linn,Ashish Pattekar,Mandana Veiseh
申请号:
US14617430
公开号:
US10039885B2
申请日:
2015.02.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A device for delivery of particles into biological tissue includes at least one conduit and a propellant source configured to release a propellant into the conduit. A source of first particles is configured to release first particles into the conduit. A source of second particles is configured to release second particles into the conduit. The second particles comprise a functional material intended to interact with the biological tissue and having a density less than a density of the first particles. The propellant source and the conduit are configured to propel the particles in a collimated stream toward the biological tissue. The first particles are configured to penetrate the biological tissue to create micropores that increase porosity of the biological tissue and the second particles configured to enter the porous biological tissue.