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DIFFERENTIATION MARKER AND DIFFERENTIATION CONTROL OF EYE CELL
专利权人:
发明人:
Takahiro Nakamura,Noriko Koizumi,Naoki Okumura,Shigeru Kinoshita,Kana Tominaga,Satoshi Kawasaki
申请号:
US15443913
公开号:
US20170202910A1
申请日:
2017.02.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to a differentiation marker and a differentiation controlling technique for an eye cell. More particularly, the present invention has attained an object of providing a differentiation marker for an eye cell among the aforementioned problems, by providing a marker for identifying a cell having a high proliferation ability among corneal endothelial cells and/or the differentiation ability of a corneal endothelial cell, the marker comprising GPR49/LGR5, as well as a detection agent or detection method for identifying a cell having a high proliferation ability among corneal endothelial cells and/or the differentiation ability of a corneal endothelial cell, comprising a substance binding to GPR49/LGR5. In addition, the present invention has attained an object of providing a differentiation controlling technique for an eye cell, by providing an agent for suppressing differentiation and/or promoting proliferation of an eye cell, comprising R-spondins.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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