A pressure unloading device for unloading pressure on a pathological prominence of the foot includes a securement and a spacer. The securement wraps around a portion of a foot and secures a spacer to a region of the foot proximate to a pathological prominence in order to unload pressure on the prominence. Pressure unloading devices can further include footwear, such as a shoe or other footwear or footwear liner having voids and/or spacers.
