Formulations are disclosed that contain one or more prebiotics and one or more probiotics. The formulations of the present invention may be used as a supplement that is also a sweetener. The supplement may be useful for anti-aging and/or anti-oxidant properties, increasing mental faculties and/or a decreasing cognitive decline, antibacterial properties, cardiovascular health properties, digestive health benefits such as being effective against irritable bowel syndrome, cognitive health benefits, mental health benefits, anti-inflammatory activity, dry skin treatment, and other benefits.