Ajay Gupta,Hyman M. Schipper,Moulay Alaoui-Jamali,Walter A. Szarek,Kanji Nakatsu,Jason Z. Vlahakis
申请号：
US13006338
公开号：
US20120020915A1
申请日:
2011.01.13
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are compounds of the general formula (I):compositions comprising an effective amount of said compounds either alone or in combination with other chemotherapeutic agents, and methods useful for treating or preventing cancer and for inhibiting tumour tissue growth. These compounds attenuate the oxidative damage associated with increased heme-oxygenase activity and can reduce cell proliferation in transformed cells. In addition, the described compounds and compositions are useful as neuroprotectants and for treating or preventing neurodegenerative disorders and other diseases of the central nervous system.
