Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme ceramide galactosyltransferase (CGT), such as, for example, lysosomal storage diseases. Examples of lysosomal storage diseases include, for example, Krabbe disease and Metachromatic Leukodystrophy.本文闡述化合物、製備該等化合物之方法、含有該等化合物之醫藥組合物及藥劑、及使用該等化合物以治療或預防與酶神經醯胺半乳糖基轉移酶(CGT)相關之疾病或病症(例如溶酶體儲積症)的方法。溶酶體儲積症之實例包括例如克拉伯病(Krabbe disease)及異染性白質失養症。無