CHRISTIAN EICKMEIER,CORNELIA DORNER-CIOSSEK,DENNIS FIEGEN,GERHARD SCHAENZLE,HOLGER ROSENBROCK,KLAUS FUCHS,NIKLAS HEINE,RICCARDO GIOVANNINI,THOMAS FOX
申请号：
BRPI1011533
公开号：
BRPI1011533A2
申请日:
2010.03.26
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The invention relates to novel 1,6-disubstituted pyrazolopyrimidinones of formula (I), in which Hc is a tetrahydropyranyl-group and R1 is the group V-W-*, whereby V and W independently of each other may be an aryl group or an heteroaryl group, which independently of each other may optionally be substituted. According to one aspect of the invention the new compounds are for use as medicaments or for the manufacture of medicaments, in particular medicaments for the treatment of conditions concerning deficits in perception, concentration, learning or memory. The new compounds are also for the manufacture of medicaments and/or for use in the treatment of e.g. Alzheimer's disease, in particular for cognitive impairment associated with Alzheimer's disease.
