PROBLEM TO BE SOLVED: To accurately measure a water removal amount with a simple configuration.SOLUTION: A blood purification device comprises: a blood purifier 120; a waste liquid pipe conduit 130 including a first branch path 131, a second branch path 132, and a third branch path 133; a dialysate pipe conduit 142; a replacement fluid pipe conduit 152; a first pump 160 that pumps out waste liquid 138 flowing through the first branch path 131 and dialysate 141 flowing through the dialysate pipe conduit 142 so that flow rates of the waste liquid and the dialysate are equal to each other; a second pump 161 that pumps out waste liquid 138 flowing through the second branch path 132 and replacement fluid 151 flowing through the replacement fluid pipe conduit 152 so that flow rates of the waste liquid and the replacement fluid are equal to each other; a third pump 162 that is connected to the third branch path 133 and pumps out waste liquid 138 flowing through the third branch path 133; a first valve 179 that opens/closes the third branch path 133; a first refuge pipe 134 through which waste liquid 138 temporarily flows; and a scale 139 that measures weight of waste liquid discharged from the waste liquid pipe conduit 130.SELECTED DRAWING: Figure 1【課題】簡易な構成で除水量を正確に測定する。【解決手段】血液浄化器120と、第1分岐路131、第2分岐路132および第3分岐路133を含む排液管路130と、透析液管路142と、補液管路152と、第1分岐路131を流れる排液138と透析液管路142を流れる透析液141とを互いに等しい流量で送り出す第1ポンプ160と、第2分岐路132を流れる排液138と補液管路152を流れる補液151とを互いに等しい流量で送り出す第2ポンプ161と、第3分岐路133に接続され、第3分岐路133を流れる排液138を送り出す第3ポンプ162と、第3分岐路133を開閉する第1バルブ179と、排液138が一時的に流れる第1退避管134と、排液管路130から排出された排液の重量を測定する秤139とを備える。【選択図】図1