De Juan Jr., Eugene,Alster, Yair,Chamow, Steven M.,Farinas, Kathleen Cogan,MacFarlane, K. Angela,Reich, Cary J.,Campbell, Randolph E.,Erickson, Signe,Bueche, Blaine
申请号：
AU2017202212
公开号：
AU2017202212B2
申请日:
2017.04.04
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2017202212B220180405.pdf#####ABSTRACT A flowable formulation for use with a therapeutic device implanted to treat an eye, the formulation comprising: a therapeutic agent having a molecular weight and a stabilizer to maintain stability of the therapeutic agent, wherein the stabilizer is selected based on the stabilizer comprising a molecular weight that is at least 10% of the molecular weight of the therapeutic agent, wherein the formulation is suitable for providing the therapeutic agent to an eye from within a therapeutic device implanted in the eye, the therapeutic device having a reservoir chamber and a porous structure, wherein the stabilizer diffuses through the porous structure at a rate that leaves an amount of the stabilizer that is sufficient to stabilize for at least one month therapeutic agent remaining in the reservoir chamber.
