The present invention provides biomembrane phase-change droplets (PCDs), including a hydrophobic liquid core and a phospholipid-consisted biomembrane encapsulating the hydrophobic liquid core, wherein the hydrophobic liquid core being evaporated by an ultrasound irradiation. The present invention also provides a drug carrier, including a biomembrane phase-change droplets and a hydrophobic drug embedded in the biomembrane of the biomembrane phase-change droplets, wherein the hydrophobic drug is present in an amount of 1~10 wt %, based on the weight of the drug carrier. The present application further provides a use thereof.本發明提供一種生物膜相變液滴(droplet),包括:一疏水性液體核心;以及具有磷脂質之一生物膜包覆疏水性液體核心;其中該疏水性液體核心經一超音波照射觸發汽化。本發明另提供一種藥物載體,包括:一生物膜相變液滴;以及一疏水性藥物,內嵌於上述之生物膜相變液滴之生物膜上;其中疏水性藥物佔藥物載體之重量百分比為1~10wt%。本發明亦提供上述生物膜相變液滴及藥物載體的用途。12‧‧‧疏水性液體核心14‧‧‧生物膜141‧‧‧磷脂質142‧‧‧膜蛋白16‧‧‧疏水性藥物20‧‧‧藥物載體
