Peter Laing;Andrew David Bacon;Gregory Gregoriadis
发明人:
Andrew David Bacon,Peter Laing,Gregory Gregoriadis
申请号:
US13128216
公开号:
US20120121689A1
申请日:
2009.11.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A liposomal siRNA composition is described. The liposomes are formed of neutral liposome forming components, and the composition comprising additionally sugar. The composition provides reduced expression of target gene, without causing systemic toxicity. The composition is produced by a dehydration-rehydration technique to provide high yields and good control of liposome size.