PAUL GILLESPIE,LI CHEN,YUN HE,FARIBORZ FIROOZNIA,TAI-AN LIN,ERIC MERTZ,SUNG-SAU SO,HONGYING YUN,ZHENSHAN ZHANG
申请号:
PT09751894
公开号:
PT2346819E
申请日:
2009.11.09
申请国别(地区):
PT
年份:
2013
代理人:
摘要:
The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein W, X, Y, and R1-R7 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.