Biphenylcarboxamide derivatives as hedgehog pathway modulators

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专利权人:

アイアールエム・リミテッド・ライアビリティ・カンパニー

发明人:

クリスティーネ・ディールクス,マルクス・ヴァルムト,ウ・シュ

申请号：

JP2010511306

公开号：

JP5373777B2

申请日:

2008.06.04

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The invention provides a method for modulating the activity of the hedgehog signaling pathway. In particular, the invention provides a method for inhibiting aberrant growth states resulting from phenotypes such as Ptc loss-of-function, hedgehog gain-of-function, smoothened gain-of-function or Gli gain-of-function, comprising contacting a cell with a sufficient amount of a compound of Formula I.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/