CELERA CORPORATION;LEIDEN UNIVERSITY MEDICAL CENTRE (LUMC) ACTING ON BEHALF OF ACADEMIC HOSPITAL LEIDEN (AZL)
发明人:
BARE, LANCE,DEVLIN, JAMES,ROSENDAAL, FRITS R.,REITSMA, PIETER H.,BEZEMER, IRENE D.
申请号:
CA2717045
公开号:
CA2717045C
申请日:
2009.03.13
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention isbased on the discovery of geneticpolymorphisms that are associated with venousthrombosis. In particular, the presentinvention relates to nucleic acid moleculescontaining the polymorphisms, variantproteins encoded by such nucleic acidmolecules, reagents for detecting thepolymorphic nucleic acid molecules andproteins, and methods of using the nucleicacid and proteins as well as methods ofusing reagents for their detection.