THE BOARD OF REGENTS OF THE UNIVERSITY OF ILLINOIS;THE UNIVERSITY OF CHICAGO
发明人:
DAUM, ROBERT, S.,BOYLE-VAVRA, SUSAN,JOHNSON, MICHAEL, E.
申请号：
EP14764384
公开号：
EP2969003A4
申请日:
2014.03.14
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Compositions and methods are provided for treating or inhibiting a bacterial infection involving at least one antibiotic and a compound that potentiates the antibiotic activity of the antibiotic. In certain embodiments the antibiotic is a beta lactam. In further embodiments, the antibiotic is oxacillin. In additional embodiments, the potentiating compound is an inhibitor of vraSR operon expression. In specific embodiments, the bacterial infection involves an antibiotic-resistant bacteria.
