Andrew Wonhee Han,Andrew Whitman Goodyear,Tarunmeet Gujral,Todd Zachary DeSantis,Karim Dabbagh
申请号:
US16610823
公开号:
US20200061152A1
申请日:
2018.05.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.