The present invention relates to use of a Toona sinensis extract. The Toona sinensis extract has an effect of preventing growth or reproduction of microorganisms and thus can be used for manufacturing an antimicrobial agent, an antiseptic, or a medicinal composition. The use of the toona sinensis extract includes the steps of: grinding dried leaves of Toona sinensis preparing a Toona sinensis solution proceeding a reaction of extracting the Toona sinensis solution and obtaining the Toona sinensis extract.COPYRIGHT KIPO 2014본 발명은 참죽나무 추출물에 관한 것으로서, 상기 참죽나무 추출물은 미생물의 생장 또는 번식을 억제하는 효능이 있으므로 항균제, 방부제 또는 의약 조성물 제조에 사용할 수 있다.