Beth Israel Deaconess Medical Center, Inc.;Janssen Vaccines &; Prevention B.V.
发明人:
Dan BAROUCH,Johanna SCHUITEMAKER,Maria Grazia PAU,Danielle VAN MANEN,Frank TOMAKA,Jennifer Anne HENDRIKS
申请号:
US16593658
公开号:
US20200030437A1
申请日:
2019.10.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compositions, vaccines and methods for inducing an immunity, including a protective immunity, against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more adenovirus 26 vectors using for priming immunization and an isolated HIV antigenic polypeptide in combination with one or more MVA vectors for boosting immunization induced strong protective immunity against infections by one or multiple clades of HIV.