TRPA1 AND TRPV4 INHIBITORS AND METHODS OF USING THE SAME FOR ORGAN-SPECIFIC INFLAMMATION AND ITCH

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专利权人:

Duke University

发明人:

Wolfgang Liedtke,Farshid Guilak

申请号：

US16391047

公开号：

US20190315700A1

申请日:

2019.04.22

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Provided are methods of treating and/or preventing dermatological disorders. Provided are methods of reducing skin inflammation, reducing pain, and/or reducing itch in a subject in need thereof. The methods may include administering to the subject an effective amount of a TRPA1 and/or TRPV4 inhibitor. Further provided are compositions including a TRPA1 and/or TRPV4 inhibitor compound in combination with a carrier, vehicle, or diluent that is suitable for topical application.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/