Hyung Jun LIM,Nok Hyun PARK,Yuri CHOI,Il-Hong BAE,Myeong Jin GOH,Jae Won YOU,Song Seok SHIN,Jon Hwan LEE
申请号:
US14883327
公开号:
US20160106864A1
申请日:
2015.10.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure relates to a drug delivery carrier containing a lipid structure or a polymer particle which is covalently bonded to a cell-penetrating AP-GRR peptide (SEQ ID NO 1) or is modified with the peptide chain containing the peptide. The present disclosure also relates to a composition containing the drug delivery carrier and a physiologically active ingredient encapsulated in the carrier. The drug delivery carrier of the present disclosure can effectively deliver macromolecules that are difficult to be delivered into cells, thereby improving the bioavailability of the macromolecules.