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Method and apparatus to coat a metal implant with electrospun nanofiber matrix
专利权人:
UNIVERSITY OF CENTRAL OKLAHOMA
发明人:
Morshed Khandaker,Shahram Riahinezhad
申请号:
US15467652
公开号:
US09809906B2
申请日:
2017.03.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention implements a set of grooves/ridges created on Ti at the circumferential direction to increase surface area of implant in contact with bone. These grooves/ridges protect nanofiber matrix (NFM) made with Polycaprolactone (PCL) electrospun nanofiber (ENF) and collagen at the groove from physiological loading. Controlled fabrication of a ridge made with titanium nitride (TiN) around the circumference of Ti is provided using a plasma nitride deposition technique. PCL ENF may be deposited along the sub-micrometer grooves using the electrospin setup disclosed. The method provides for fabrication of microgroove on Ti using machining or TiN deposition and filling the microgrooves with the NFM. This method has proven through experimentation to be successful in increasing in vivo mechanical stability and promoting osseointegration on Ti implants. The immobilization of MgO NP and FN with the PCL-CG NFM on microgrooved Ti as provided in the invention optimizes biological performances of Ti.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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