COMPOSITIONS THERAPEUTIQUES ET PROCEDES D'ADMINISTRATION CIBLEE DE MOLECULES BIOACTIVES PAR DES MINICELLULES BACTERIENNES BASEE SUR DES MOLECULES DE CIBLAGE CONTENANT UN FRAGMENTFC ET DES ANTICORPS

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专利权人:

VAXIION THERAPEUTICS; INC.

发明人:

GIACALONE, MATTHEW,NEWMAN, MICHAEL J.

申请号：

CA2827443

公开号：

CA2827443A1

申请日:

2012.02.15

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The present application relates to the use of bacterial minicells as targeted delivery agents in vivo and in vitro. Described herein are genetically engineered eubacterial minicells designed to preferentially target and deliver therapeutically relevant agents using a minicell surface coupling molecule capable of binding and displaying antibodies or other Fc-containing targeting moiety fusions and conjugates.

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http://www.ckcest.cn/home/