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LIVER-SPECIFIC DELIVERY-BASED ANTI-HEPATITIS C PRODRUG NUCLEOSIDE CYCLO-PHOSPHATE COMPOUND AND USES THEREOF
专利权人:
ZHEJIANG PALO ALTO PHARMACEUTICALS;INC
发明人:
Zhijian XI,Huaqiang XU,Chunping LU,Zhongshan WU,Feng SUN
申请号:
US16656595
公开号:
US20200048299A1
申请日:
2019.10.18
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are a liver specific delivery (LSD)-based antiviral prodrug nucleoside cyclophosphate compound and uses thereof. Specifically, this application provides a compound of formula (I), or an isomer, a pharmaceutically acceptable salt, a hydrate, a solvate or a pharmaceutical composition thereof. This application also provides an application of the compound alone or in combination with other antiviral drugs in the treatment for viruses, particularly hepatitis C virus (HCV).
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