Jan Weiler,William Chutkow,Jeremy Lee Baryza,Andrew Krueger,Junping Zhao
申请号:
US16269282
公开号:
US20190233817A1
申请日:
2019.02.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure relates to compositions and methods for treating APOC3-related diseases such as: hypertriglyceridemia (e.g., Type V Hypertriglyceridemia), abnormal lipid metabolism, abnormal cholesterol metabolism, atherosclerosis, hyperlipidemia, diabetes, including Type 2 diabetes, obesity, cardiovascular disease, and coronary artery disease, among other disorders relating to abnormal metabolism or otherwise, using a therapeutically effective amount of a RNAi agent to APOC3.