Method for the identification of transiently Foxp3 negative regulatory T-cells from human peripheral blood

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专利权人:

发明人:

申请号：

EP14004388.6

公开号：

EP3037816A1

申请日:

2014.12.23

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The invention relates to a method for determination of the frequency of regulatory T-cells in samples obtained from human blood and to methods for the preparation of compositions comprising predetermined amount of regulatory T-cells. The invention is based on the conception that a large fraction of regulatory T-cells present in human peripheral blood do not express detectable amounts of Foxp3, the master transcription factor used for identification of regulatory T-cells, as a result of cytokine deprivation outside of the tissue context.

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中国工程科技知识中心

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