Moseley, Scott Edward,Denker, Andrew E.,Pan, Wei-Jian
申请号:
AU2018243320
公开号:
AU2018243320A1
申请日:
2018.03.29
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The disclosure features methods for treating hypophosphatasia (HPP) in a patient (e.g., an adult having HPP, such as an adult having pediatric-onset HPP, or an adolescent having HPP) exhibiting decreased pyrophosphate (PPi) or pyridoxal 5'-phosphate (PLP) concentrations in, e.g., a plasma sample, physical impairments, or decreased walking ability by administering a soluble alkaline phosphatase (sALP) to the patient.