Siva Ram Kiran Vaka,Namdev B. Shelke,Dipen Desai,Wantanee Phuapradit,Navnit H. Shah
申请号：
US16445110
公开号：
US20190374473A1
申请日:
2019.06.18
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Extended release pyridostigmine dosage forms, suitable for maintaining stable plasma concentrations with reduced or minimized initial burst release/dose dumping of pyridostigmine, are provided. The dosage forms include matrix tablets, gastroretentive tablets, and pellets, the latter being suitable for dosing in capsules, tablets, and sachets, as well as for sprinkling on foodstuffs. The disclosure also provides methods for improving patient compliance by administering once-a-day extended release pyridostigmine bromide dosage forms that provide a superior controlled drug release.
