PROBLEM TO BE SOLVED: To provide a hyaluronic acid synthesis promoter which contains a substance promoting the production of hyaluronic acid with safe and without side effects even used continuously, is used for preventing or treating skin exacerbation which develops in association with aging, such as spots, wrinkles, roughness, and sagging of the skin, or atopic dermatitis, psoriasis or ichthyosis, rheumatism or purulence and gouty arthritis, and burn and to provide an external preparation for skin, a food and drink, a medical supply, and a feed containing thereof.SOLUTION: The invention provides a hyaluronic acid synthesis promoter comprising cryptoxanthin and/or a derivative thereof, preferably the cryptoxanthin and/or a derivative thereof is derived from citrus.
