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Methods of identifying responders to dopamine agonist therapy and treating metabolic conditions thereof
专利权人:
Anthony H. Cincotta
发明人:
Anthony H. Cincotta
申请号:
US12931859
公开号:
US08137992B2
申请日:
2011.02.11
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to a method of identifying patients to be treated by dopamine agonist therapy comprising the step of analyzing a plasma or urine sample from said patient for concentrations of norepinephrine (NE), norepinephrine metabolites (NE metabolites), dopamine, dopamine metabolites, serotonin, serotonin metabolites, or fasting triglycerides, wherein one or more of: (a) NE metabolites, (b) NE/NE metabolites:dopamine/dopamine metabolites, (c) NE and serotonin, (d) NE/NE metabolites and serotonin, (e) NE and serotonin metabolites, (f) NE/NE metabolites and serotonin metabolites, or (g) NE is/are greater than about 30% over normal level or dopamine/dopamine metabolites are less than about 30% below normal or fasting triglycerides are greater than about 150 mg/dl and/or said patient has blood pressure of greater than about 135/85 mm Hg. The present invention is also directed to treating identified patients with dopamine agonist therapy.
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中国工程科技知识中心
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