Eva M. Harth,James E. Crowe, JR.,Kui Huang,Sharon K. Hamilton,Heidi E. Hamm,Bryan Voss
申请号：
US14637105
公开号：
US20150315174A1
申请日:
2015.03.03
申请国别(地区):
US
年份:
2015
代理人:
摘要：
In accordance with the purpose(s) of the invention, as embodied and broadly described herein, the invention, in one aspect, relates to compounds comprising the structure:and at least one guanidinium residue, wherein m is zero or a positive integer. Also disclosed are methods of preparing the disclosed compounds. Also disclosed are methods of intracellular delivery comprising administering the disclosed compounds and compositions to a subject. Also disclosed are pharmaceutical compositions comprising a therapeutically effective amount of one or more compounds or compositions of the invention and a pharmaceutically acceptable carrier. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
