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ONCOLYTIC ADENOVIRUS ENCODING A B7 PROTEIN
专利权人:
发明人:
CHAMPION BRIAN ROBERT,BROMLEY ALICE CLAIRE NOEL
申请号:
IN201818007792
公开号:
IN201818007792A
申请日:
2018.03.01
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present disclosure provides a replication competent oncolytic adenovirus with selectivity for cancer cells, wherein the adenovirus comprises a transgene under the control of a promoter endogenous to the virus, wherein the transgene comprises a DNA sequence encoding a B7 protein or an active fragment thereof, compositions comprising same, methods of generating the viruses, and use of the viruses and compositions in treatment, particularly in the treatment of cancer.
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中国工程科技知识中心
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