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Methods, systems and compositions and associated screening methods for cancer diagnosis, treatment and / or prevention, and / or suppression of invasion / metastasis
专利权人:
国立大学法人;東京大学
发明人:
村上 善則,増田 万里
申请号:
JP2006248743
公开号:
JP5131946B2
申请日:
2006.09.13
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
<;P>;PROBLEM TO BE SOLVED: To provide utterly novel techniques for diagnosis, treatment and/or prevention of cancers (especially small cell lung cancer) and/or for inhibition of invasion or metastasis of cancers. <;P>;SOLUTION: The invention provides a method of controlling invasion or metastasis of cancers, which is a method including (A) a step of controlling a molecular pathway of TSLC1 (tumor-suppressor gene in human non-small-cell lung cancer). The invention further provides a method of screening a regulator for metastasis and/or invasion of cancers, the method comprising (A) a step of providing candidate substances; (B) a step of providing the candidate substances to an assay system for the molecular pathway of TSLC1; and (C) a step of identifying a regulator for the molecular pathway of TSLC1 among the candidate substances, and determining the regulator as a regulator for invasion and/or metastasis of cancers. <;P>;COPYRIGHT: (C)2007,JPO&INPIT
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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