The disclosed embodiments relate to a mitral or tricuspid heart valve prosthesis that includes. An expansible tubular frame and a prosthetic valve mounted on the frame. The frame includes an atrial portion, a ventricular portion, and an annular portion located between said atrial and ventricular portions, wherein: the atrial portion is made up of three or four metal-wire extensions, regularly distributed on the circumference of said atrial portion and projecting from said annular portion, each extension being made up of a single upside-down U-shaped or V-shaped wire and the various extensions being substantially part of an imaginary truncated sphere placed above said annular portion. The annular portion is made up of diamond meshes which comprise anchoring points； and said ventricular portion is made up of three or four extensions equivalent to the extensions, substantially contained inside an imaginary ovoid shape placed under said annular portion.
