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Formulation comprising 1 h - quinazoline - 2, 4 - dione ampa receptor antagonists, in the form of immediate release tablets and preparation thereof
专利权人:
NOVARTIS AG
发明人:
ZIELINSKI JOSEPH LAWRENCE,VRETTOS JOHN,JI QIN,PATEL SUBASH
申请号:
NZ60071710
公开号:
NZ600717A
申请日:
2010.12.21
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed herein is a tablet comprising a hydroxypropylcellulose and an active ingredient selected from compounds of Formula (I) and salts thereof: wherein R1 represents CF3, CHF2, CH2F, CH3CHF-, CH3CF2-, ethyl or iso-propyl and R2 represents alkyl substituted by one or more substituents, the substituents being defined in the specification, and whereby the heterocycle is bound to the phenyl ring by a carbon-atom. Also disclosed is a process for preparing the above tablet. In one embodiment the compound it N-{ 6-[3-(1-hydroxy-ethyl)-phenyl]-2,4-dioxo-7-trifluoromethyl-1,4-dihydro-2H-quinazolin-3-yl} -methanesulfonamide.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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