Humanized and chimeric anti-factor Bb antibodies and uses thereof

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专利权人:

NovelMed Therapeutics; Inc.

发明人:

Rekha Bansal

申请号：

US14390632

公开号：

US09243070B2

申请日:

2013.04.02

申请国别(地区):

US

年份:

2016

代理人:

摘要：

A method of inhibiting complement activation mediated by Bb inhibitors in a subject includes administering a Bb inhibitor to the subject to inhibit at least one of Bb binding to factors B and properdin, inhibit C3 cleavage, inhibit the activation of neutrophils, monocytes, platelets, and endothelium； or inhibit the formation of C3a, C5a, and MAC.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/